Search results

CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity

Madison B. Adolph, Atharv S. Garje, Swati Balakrishnan, et al.

Selected by Jessica Chevallier, Pierre Caron

Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis

Camille Gelot, Marton Tibor Kovacs, Simona Miron, et al.

Selected by Pierre Caron

Telomere-to-telomere human DNA replication timing profiles

Dashiell J. Massey, Amnon Koren

Selected by Jennifer Ann Black

A live-cell marker to visualize the dynamics of stable microtubules

Klara I. Jansen, Mithila Burute, Lukas C. Kapitein

Selected by Niveda Udaykumar

Biomimetic, smart and multivalent ligands for G-quadruplex isolation and bioorthogonal imaging

Francesco Rota Sperti, Thibaut Charbonnier, Pauline Lejault, et al.

Selected by Jennifer Ann Black

CENP-A chromatin prevents replication stress at centromeres to avoid structural aneuploidy

Simona Giunta, Solène Hervé, Ryan R. White, et al.

Selected by Sree Rama Chaitanya

ARID1A regulates R-loop associated DNA replication stress

Shuhe Tsai, Emily Yun-Chia Chang, Louis-Alexandre Fournier, et al.

Selected by Sree Rama Chaitanya

SF3B1-targeted Splicing Inhibition Triggers Global Alterations in Transcriptional dynamics and R-Loop Metabolism

Daisy Castillo-Guzman, Stella R. Hartono, Lionel A. Sanz, et al.

Selected by Sree Rama Chaitanya

Live-cell imaging shows uneven segregation of extrachromosomal DNA elements and transcriptionally active extrachromosomal DNA clusters in cancer

Eunhee Yi, Amit D. Gujar, Molly Guthrie, et al.

Selected by Sree Rama Chaitanya

Functional diversification of Ser-Arg rich protein kinases to control ubiquitin-dependent neurodevelopmental signalling

Francisco Bustos, Anna Segarra-Fas, Gino Nardocci, et al.

Selected by Sree Rama Chaitanya

Single-molecule live cell imaging of the Smc5/6 DNA repair complex

Thomas J. Etheridge, Desiree Villahermosa, Anja Irmisch, et al.

Selected by Jennifer Ann Black

Pal stabilises the bacterial outer membrane during constriction by a mobilisation-and-capture mechanism

Joanna Szczepaniak, Peter Holmes, Karthik Rajasekar, et al.

Selected by Hannah Behrens